Chronic pancreatitis (CP) is historically defined as an irreversible inflammatory condition of the pancreas leading to varying degrees of exocrine and endocrine dysfunction. Recently however, the paradigm for the diagnosis has changed in that it breaks with the traditional clinicopathologic-based definition of disease, focusing instead on diagnosing the underlyingpathologic process early in the disease course andmanaging the syndromemore holistically to change the natural course ofdisease and minimize adverse disease effects.
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